This trial is recruiting individuals with chronic cervical (neck area) spinal cord injuries to test the effect of cervical electrical stimulation (CES) on hand function. The stimulation is non-invasive — skin-surface electrodes are placed on the neck. The goal of the study is strengthen preserved nerve circuits to hand muscles, a top priority for individuals with cervical SCI. In this two-part study, CES will first be applied in combination with transcranial magnetic stimulation (non-invasive surface stimulation of the brain) and peripheral nerve stimulation (non-invasive electrical stimulation of nerves in the upper extremities). Information derived from these initial stimulations will determine the CES settings for each participant. Active rehabilitation of hands and wrists will also be included to enhance voluntary muscle activation. This study may lead to the clinical use of CES to improve the effects of physical exercise.
Traumatic
Type
Details
Attachment of stimulation electrodes at the skin surface of the neck Attachment of recording electrodes at the skin surface of the upper extremity CES combined with transcranial magnetic stimulation or peripheral nerve stimulation at rest CES while performing hand and wrist movements The participant will complete the various stimulation, movement activities and outcome assessments in a single visit to the study center.
Main benefits
Arm/hand function
Additional benefits
General health
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more