About this trial

This is a clinical trial investigating the effects of spinal cord stimulation combined with physical therapy on sensory, motor and autonomic functions in individuals with chronic spinal cord injuries. Spinal cord stimulation (SCS) is a technique that uses an electric current to change the activity of the nerves in the spinal cord. This study uses skin-surface electrodes placed above the spinal cord. Physical therapy targeting the arms and legs is included (activity-based rehabilitation). If included in the study, participants will undergo spinal cord stimulation with electrodes applied to the skin, as well as arm and leg physical therapy. There are three treatment arms, including 1) those with complete cervical (neck area) injuries; 2) those with complete motor paraplegia (chest level); and 3) those with incomplete injuries. Researchers want to see if stimulation plus physical therapy can cause lasting improvements in sensory, motor, respiratory or autonomic function, which might lead to a greater functional independence and quality of life for participants.