| NCT06906536 | Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function | University of Colorado, Boulder | | - Age 18 - 75 yrs
- Level C2-L5
AIS A, B, C, D- ≥ 1 years
- NOT have metal implants in the head, or pacemaker
| By invitation | 100 | NA | Drug | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Serum Biomarker
| 4 days | 01 March 2024 | 02 April 2025 | 1 | |
| NCT06990412 | A Clinical Trial to Evaluate the Safety and Efficacy of an Implantable Wireless Brain-Computer Interface（BCI）System NEO in Patients With Tetraplegia | Neuracle Medical Technology(Shanghai) Co.,Ltd. | | - Age 18 - 65 yrs
- Level C1-T1
AIS - ≥ 1 years
- NOT have already been implanted with medical devices that deliver electrical energy to the central nervous system
| Recruiting soon | 32 | NA | Technology | Arm/hand function | - Action Research Arm Test (ARAT)
- Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
| 6 months | 20 May 2025 | 25 May 2025 | 2 | |
| NCT06971510 | Exoskeleton Training on Balance Control and Turning in Ambulation in Individuals With Incomplete Spinal Cord Injury | Hong Kong Metropolitan University | | - Age 18 - 65 yrs
- Level C1-L2
AIS C, D- ≥ 6 months
- be able to walk independently at least 2 meters.
- be between 5'0" and 6'4" tall
| Active | 32 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Falls Efficacy Scale (FES, Tinetti)
- Modified Functional Reach Test (mFRT)
- Physical Activity Scale for Individuals with Physical Disabilities (PASIPD)
- Short Form 36 (SF-36)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 4 months | 01 June 2024 | 14 May 2025 | 3 | |
| NCT06981338 | Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation | Institut Guttmann | | - Age 16 - 70 yrs
- Level C1-T12
AIS A, B, C- 1 years - 5 years
| Recruiting soon | 10 | PHASE1, PHASE2 | Biological/cell based | General health | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- International Standards to Autonomic Function after SCI (ISAFSCI)
- Motor Evoked Potentials (MEPs)
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
| 2 years | 01 September 2025 | 20 May 2025 | 1 | |
| NCT07024407 | A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton. | Ashibio Inc | | - Age 18 - 89 yrs
- Level C1-S5
AIS - ≥ 10 days
| Recruiting | 10 | PHASE1, PHASE2 | Drug | General health | | 13 weeks | 14 May 2025 | 17 June 2025 | 1 | |
| NCT06828653 | Comparing Digitally and Traditionally Made Ankle Foot Orthoses | Holland Bloorview Kids Rehabilitation Hospital | | - Age ≥ 8 yrs
- Level C1-S5
AIS - All
- Require the use of an AFO to improve physical functioning
- Be able to ambulate independently
- Meet requirements for AFO funding by the Assistive Device Program in Ontario, Canada
| Recruiting | 50 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- Goal Attainment Scaling (GAS) score
- Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST)
- Timed Up and Go Test (TUG)
| 14 weeks | 05 September 2025 | 14 February 2025 | 2 | |
