| NCT07488793 | Remote Ischemic Conditioning for PwSCI | Washington University School of Medicine | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
| Recruiting | 24 | NA | Technology | General health | | 8 weeks | 23 February 2026 | 23 March 2026 | 1 | |
| NCT07472985 | Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury II (PROMPT-SCI II) Trial | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | | - Age ≥ 18 yrs
- Level C1-L2
AIS A, B, C- ≤ 7 days
- have had spine surgery performed within 48 hours of injury
- NOT be intubated and mechanically ventilated
| Recruiting | 102 | NA | Rehabilitation | General health | - Adverse Events (AEs)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Penn Spasm Frequency Scale (PSFS)
- Short Form 36 (SF-36)
- Spinal Cord Assessment Tool for Spastic Reflexes (SCATS)
- Spinal Cord Independence Measure (SCIM)
| 1 year | 09 March 2026 | 16 March 2026 | 1 | |
| NCT07465302 | Treating Spinal Cord Injury With Early Normobaric Hyperoxia | University of Florida | | - Age 18 - 85 yrs
- Level C1-T12
AIS A, B, C- ≤ 24 null
- need mechanical ventilation
| Recruiting | 12 | PHASE2 | Drug | General health | | 6 months | 15 April 2026 | 11 March 2026 | 1 | |
| NCT07461259 | Safety and Feasibility of TWIICE Rise - Phase 2 | TWIICE | | - Age 18 - 70 yrs
- Level C5-L5
AIS - ≥ 6 months
- NOT have a pacemaker, defibrillator, drug delivery pump, or other electrical devices if malfunctions could lead to serious adverse events
- NOT have a history of severe neurological injuries other than spinal cord injury (MS, CP, ALS, TBI, Stroke)
- NOT have a history of myocardial infarction
| Recruiting | 15 | NA | Rehabilitation | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- Blood Pressure and Heart Rate Regulation
- Numeric Pain Rating Scale
- Timed Up and Go Test (TUG)
| 16 weeks | 25 July 2023 | 10 March 2026 | 1 | |
| NCT07457645 | Safety and Efficacy of High-Channel Implanted BCI for Motor Function Improvement in Tetraplegia Patients | Shanghai Zhongshan Hospital | | - Age 18 - 65 yrs
- Level C1-T1
AIS - ≥ 6 months
| Recruiting soon | 10 | NA | Technology | Arm/hand function | - Ashworth and Modified Ashworth Scale (MAS)
- Manual Muscle Test (MMT)
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- Pain Visual Analog Scale (VAS)
| 9 months | 15 May 2026 | 09 March 2026 | 1 | |
| NCT07397559 | Spatiotemporal tSCS in Spinal Cord Injury | Washington University School of Medicine | | - Age 16 - 65 yrs
- Level C3-T12
AIS C, D- ≥ 12 months
- NOT have implanted devices (baclofen pump, epidural spinal stimulator, cardiac defibrillator, pace-maker, etc.)
- be able to voluntarily contract (motor score ≥ 1) at least two leg muscles (visual or palpable contraction)
| Recruiting | 48 | NA | Technology | Standing/walking/mobility | | 0 days | 19 January 2026 | 09 February 2026 | 1 | |
